If humans encountered this situation, there were undoubtedly only a few things they could do.
First was to exterminate all the culprits—the World Tree.
A planet is indeed vast, but for the technological level of humans, it was only a matter of some extra effort; wanting to completely eradicate a species was not particularly difficult.
However, such massive plants, as an important link in the ecological chain, could even be described as a pillar-like existence. If completely eradicated, it would undoubtedly lead to a massive biological extinction, with countless animals and insects starving to death.
In this way, the end result seemed no different. Even because of human intervention, the massive biological extinction would occur earlier.